What do mast cells release to combat allergies?

Mast cells are a type of white blood cell that play a crucial role in the body’s immune response, particularly in allergic reactions. When an allergen is encountered, mast cells become activated and release a variety of chemical mediators. The primary substance that they release in response to allergens is histamine.

Histamine is a potent vasodilator, meaning it enlarges blood vessels, and it increases vascular permeability. This leads to common allergy symptoms such as swelling, redness, and itching. Histamine release can also cause bronchoconstriction and increased mucus production, contributing to respiratory symptoms that are characteristic of allergic reactions.

Understanding the role of histamine helps clarify its significance in allergy management and treatment options. Antihistamines, for instance, are commonly used to block the effects of histamine and alleviate allergy symptoms. This is why histamine is recognized as the correct component released by mast cells to combat allergies.